Ex situ machine perfusion strategies in liver transplantation
نویسندگان
چکیده
منابع مشابه
Ex Situ Normothermic Machine Perfusion of Donor Livers.
In contrast to conventional static cold preservation (0-4 °C), ex situ machine perfusion may provide better preservation of donor livers. Continuous perfusion of organs provides the opportunity to improve organ quality and allows ex situ viability assessment of donor livers prior to transplantation. This video article provides a step by step protocol for ex situ normothermic machine perfusion (...
متن کاملSuccessful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion
We report the successful transplantation of a pair of human kidneys that were declined for transplantation due to inadequate in situ perfusion but subsequently transplanted after perfusion and assessment using ex vivo normothermic perfusion (EVNP). The kidneys were from a 35-year-old man, a donation after circulatory death donor. Both kidneys were declined by all UK transplant centers. On arriv...
متن کاملEx situ liver resection for unresectable tumors.
Primary and secondary liver tumors are among the most common tumors in humans. Two surgical approaches may be used to address these tumors: liver transplantation and liver resection. However, some tumors cannot be treated by conventional techniques or liver transplantation due to poor intraoperative exposure, limitations of indication standards, and/or other complex factors. To overcome these p...
متن کاملNormothermic ex vivo allograft blood perfusion in clinical heart transplantation.
BACKGROUND Cold ischemia associated with cold static storage is an independent risk factor for primary allograft failure and survival of patients after orthotopic heart transplantation. The effects of normothermic ex vivo allograft blood perfusion on outcomes after orthotopic heart transplantation compared to cold static storage have been studied. METHODS In this prospective, nonrandomized, s...
متن کاملMyocardial perfusion characteristics during machine perfusion for heart transplantation.
BACKGROUND Optimal parameters for machine perfusion preservation of hearts prior to transplantation have not been determined. We sought to define regional myocardial perfusion characteristics of a machine perfusion device over a range of conditions in a large animal model. METHODS Dog hearts were connected to a perfusion device (LifeCradle, Organ Transport Systems, Inc, Frisco, TX) and cold p...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2019
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2018.09.019